In this respect, the dermal papilla can be said to resemble the root of a plant. Hypertrichosis is not so prevalent in beckers nevus. The medical literature reports the treatment of hyperpigmentation with inconsistent results, and, in our experience, the response in reducing pigmentation is poor and transient at best. A becker naevus nevus in american spelling is a lateonset epidermal naevus or birthmark occurring mostly in males. Becker nevus syndrome and ipsilateral breast hypoplasia. Beckers nevus genetic and rare diseases information center. Molecular findings provide proof that the hypothesis of paradominant inheritance was. Becker s nevus poses a significant esthetic problem. Becker nevus is thought to be an androgendependent lesion with increased androgen sensitivity and receptor density within the lesion. Cutaneous examination and histopathological examination confirmed the diagnosis of beckers. Common terms, including mole, birthmark, and beauty mark, are used to describe nevi, but these terms do not distinguish specific. It typically presents unilaterally and is frequently associated with overlying hypertrichosis. Becker nevus syndrome bns is a rare epidermal nevus syndrome characterized with becker nevus and ipsilateral breast gland hypoplasia or other skin, skeletal andor muscle tissue disorders. Abstract becker nevus has been considered a cutaneous marker of underlying soft tissue and skeletal abnormalities, such as hidden spina bifida.
A prospective study demonstrated the superiority of an er. Becker nevus bn or becker melanosis is a cutaneous hamartoma characterized by a large, unilateral, hyperpigmented area with irregular borders and coarse dark terminal hairs. Use someone external from your accountant annually. Beckers nevus, postinflammatory hyperpigmentations, melasma and nevus spilus. Pdf neurocutaneous disorders are a heterogeneous group of conditions. Beckers nevus is a noncancerous, large, brown birthmark occurring mostly in males. Although the becker nevus syndrome bns is primarily defined as a becker nevus bn in association with ipsilateral breast hypoplasia or musculoskeletal malformation, there are case reports about various associated malformations. Beckers nevus is a skin disorder predominantly affecting males. Becker s nevus is a relatively common cutaneous hamartoma, but is often overlooked or misdiagnosed. Becker nevus syndrome is a phenotype characterized by the fundamental presence of becker s nevus with ipsilateral hypoplasia of the breast or other skin, skeletal. Nevus sebaceus ns and becker s nevus bn are two variants of epidermal nevi.
Becker s nevus, a unilateral hairy hyperpigmented cutaneous hamartoma, which usually appears in adolescence, has been described along with cutaneous epidermal and dermal nevus and structural abnormalities skeletal changes and breast hypoplasia. It is due to an overgrowth of the epidermis upper layers of the skin, pigment cells melanocytes and hair follicles. Intracranial cavernoma and speckled lentiginous nevus. All structured data from the file and property namespaces is available under the creative commons cc0 license. Dermoscopic features of congenital melanocytic nevus and becker nevus in an adult male population. It is of interest because since one of its entities, becker s nevus, was defined by becker in 1949, several cases have been reported with underlying anomalies which suggests that the nevus could be one symptom of an unknown. Female patients usually seek medical treatment for the thoracic nevus andor breast hypoplasia and the classic treatment consists of breast augmentation using. Pdf mosaic neurocutaneous disorders and their causes. We conducted a systematic literature research about bns and.
Hypertrichosis could be treated independently, but the. Beckers nevus and lethal betaactin mutations sciencedirect. Prevalence and clinical characteristics of beckers nevi in young. The purpose of this study was to identify and analyze the common manifestations of the bns. He also complained of increased growth of hair over the lesion.
Beckers nevus histopathology loma linda dermatopathology. It develops during childhood or adolescence on the shoulders or upper trunk, occasionally elsewhere. Beckers nevus, beckers nevus syndrome, nevoid melanosis. It is normally found on the shoulders and chest, although it can appear in other areas. Becker s nevus is a sharply demarcated tan to brown patch or slightly raised verrucous plaque that most commonly appears on the shoulder, chest, or upper back. Files are available under licenses specified on their description page. Request pdf intracranial extraaxial cavernous hem angiomas. Becker nevus is a hyperpigmented hamartoma with an irregular outline and often hairy. Ns clinically presents as a yellowishorange, hairless plaque on the scalp, face, or neck, while bn presents as a tantobrown hyperpigmented, sometimes hypertrichotic, plaque typically on the chest and shoulder. Becker understands preparing for the cpa exam requires an enormous investment of time and energy. Beckers nevus syndrome in a pediatric female patient.
Suncoast university and universidad del rosario, bogota, colombia. Yag laser showed complete clinical clearance, while a clearance of greater than 50% occurred in 100% of the subjects. The purpose of this study was to determine the prevalence of lesional hypertrichosis. As this was apparently the first documented cooccurrence of the two diseases, there is so far no evidence of higher malignancy rates in becker s nevi versus normal skin. Beckers nevus and ipsilateral breast hypoplasia androgen. Becker nevus of the leg with lipoatrophy dermatology. The becker s nevi in the younger children were often hairless. Report of three cases abstract becker s nevus is a relatively frequent pigmentary disorder.
Soeprono teaches and practices dermatopathology at loma linda university, school of medicine, department of dermatology. Of the nine melanomas, five were in the same body area as the becker s nevus, with only one occurring within the nevus itself. In this series only 5% of the children had becker s nevus syndrome and in these cases becker s nevus was present from birth patrizi et al. Soepronos textbook is available on and includes detailed information on over 600 entities and includes four dvd diskettes with highresolution images that provide a virtual dermatopathology reference and guide. Nevus or nevi if multiple is a nonspecific medical term for a visible, circumscribed, chronic lesion of the skin or mucosa. This nevus usually begins during the second decade of life as a circumscribed, hyperpigmented patch with irregular outline that gradually enlarges with associated hypertrichosis, developing several years later. Becker s nevus syndrome is an association of becker s nevus with unilateral breast hypoplasia and muscle, skin, andor skeletal abnormalities. The becker s nevus is androgendependent, becoming more prominent and developing coarse hair after puberty in males. It can be present at birth, but is usually first noticed around puberty. Beckers nevus on the forearma case report semantic scholar.
Becker nevus presents most commonly as a patchy hyperpigmentation with dark hairs on the upper arms or the shoulder girdle of male patients. Beckers nevus cases diagnosed, with a prevalence of 6. It is a syndrome described in 1997 and characterized by the presence of a becker nevus in association with unilateral hypoplasia of breast or other cutaneous, muscular or skeletal defects. Evaluation 2 years after treatment showed that 54% of subjects treated with the er. We here report a case of a 15 yearold female who presented with bilateral becker s nevus over her groins, thighs, vulva, and in front of the neck from the age of 5 years. Becker s nevus syndrome is part of the epidermal nevus syndromes and has been described with a phenotype that includes becker s nevus, ipsilateral breast hypoplasia, and variable skeletal malformations. A case of nevus lipomatosus superficialis with features of a spindle cell lipoma. Acquired unilateral lesion found in adolescent males second or third decade. Becker s nevus syndrome is the name given to the association of these lesion with other ipsilateral oseous, musclular or cutaneous defects.
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